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mda mb 468 cell lines  (ATCC)
99
ATCC mda mb 468 cell lines
In vitro antitumor efficacy and effector function of mRNA CAR T cells (A) Enlarged schematic of the real-time cytotoxicity assessment (RTCA) workflow. (B) <t>Cytolysis</t> <t>of</t> <t>MDA-MB-468</t> cells at 24 h across various E:T ratios. (C and D) Cytokine secretion (IL-2, TNF-α, IFN-γ, and CD4/CD8 subset distribution). (E–G) Flow cytometry analysis of exhaustion markers. (H) Schematic illustration of the mechanism for mRNA-CAR delivery into T cells via lipid nanoparticles. (I) Cytolysis of SKOV3 cells at 24 h across various E:T ratios. (J) Supernatant cytokine secretion (IL-2, TNF-α, and IFN-γ) following coculture with SKOV3 cells. (K–N) Flow cytometry analysis of CD4/CD8 T cell subset distribution and exhaustion markers (LAG-3, TIM-3 and PD-1) on T cells over time in SKOV3 cocultures. Data represent mean ± SD from three independent biological donors. Data are presented as mean ± SD, n = 3 (independent biological replicates). The statistical analysis was measured by paired two-tailed t tests. ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p ≤ 0.0001, and ns indicates no significance.
Mda Mb 468 Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mda-mb-468/MDA-MB-468/pmc13673102-272-12-7
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mda mb 468 cell lines - by Bioz Stars, 2026-10
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mda mb 468  (DSMZ)
95
DSMZ mda mb 468
In vitro antitumor efficacy and effector function of mRNA CAR T cells (A) Enlarged schematic of the real-time cytotoxicity assessment (RTCA) workflow. (B) <t>Cytolysis</t> <t>of</t> <t>MDA-MB-468</t> cells at 24 h across various E:T ratios. (C and D) Cytokine secretion (IL-2, TNF-α, IFN-γ, and CD4/CD8 subset distribution). (E–G) Flow cytometry analysis of exhaustion markers. (H) Schematic illustration of the mechanism for mRNA-CAR delivery into T cells via lipid nanoparticles. (I) Cytolysis of SKOV3 cells at 24 h across various E:T ratios. (J) Supernatant cytokine secretion (IL-2, TNF-α, and IFN-γ) following coculture with SKOV3 cells. (K–N) Flow cytometry analysis of CD4/CD8 T cell subset distribution and exhaustion markers (LAG-3, TIM-3 and PD-1) on T cells over time in SKOV3 cocultures. Data represent mean ± SD from three independent biological donors. Data are presented as mean ± SD, n = 3 (independent biological replicates). The statistical analysis was measured by paired two-tailed t tests. ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p ≤ 0.0001, and ns indicates no significance.
Mda Mb 468, supplied by DSMZ, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mda-mb-468/MDA-MB-468/pm42838938-232-21-23
Average 95 stars, based on 1 article reviews
mda mb 468 - by Bioz Stars, 2026-10
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mda mb 468  (ATCC)
99
ATCC mda mb 468
In vitro antitumor efficacy and effector function of mRNA CAR T cells (A) Enlarged schematic of the real-time cytotoxicity assessment (RTCA) workflow. (B) <t>Cytolysis</t> <t>of</t> <t>MDA-MB-468</t> cells at 24 h across various E:T ratios. (C and D) Cytokine secretion (IL-2, TNF-α, IFN-γ, and CD4/CD8 subset distribution). (E–G) Flow cytometry analysis of exhaustion markers. (H) Schematic illustration of the mechanism for mRNA-CAR delivery into T cells via lipid nanoparticles. (I) Cytolysis of SKOV3 cells at 24 h across various E:T ratios. (J) Supernatant cytokine secretion (IL-2, TNF-α, and IFN-γ) following coculture with SKOV3 cells. (K–N) Flow cytometry analysis of CD4/CD8 T cell subset distribution and exhaustion markers (LAG-3, TIM-3 and PD-1) on T cells over time in SKOV3 cocultures. Data represent mean ± SD from three independent biological donors. Data are presented as mean ± SD, n = 3 (independent biological replicates). The statistical analysis was measured by paired two-tailed t tests. ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p ≤ 0.0001, and ns indicates no significance.
Mda Mb 468, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mda-mb-468/MDA-MB-468/pm42826203-281-8-25
Average 99 stars, based on 1 article reviews
mda mb 468 - by Bioz Stars, 2026-10
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mda mb 468 cell line  (ATCC)
99
ATCC mda mb 468 cell line
In vitro antitumor efficacy and effector function of mRNA CAR T cells (A) Enlarged schematic of the real-time cytotoxicity assessment (RTCA) workflow. (B) <t>Cytolysis</t> <t>of</t> <t>MDA-MB-468</t> cells at 24 h across various E:T ratios. (C and D) Cytokine secretion (IL-2, TNF-α, IFN-γ, and CD4/CD8 subset distribution). (E–G) Flow cytometry analysis of exhaustion markers. (H) Schematic illustration of the mechanism for mRNA-CAR delivery into T cells via lipid nanoparticles. (I) Cytolysis of SKOV3 cells at 24 h across various E:T ratios. (J) Supernatant cytokine secretion (IL-2, TNF-α, and IFN-γ) following coculture with SKOV3 cells. (K–N) Flow cytometry analysis of CD4/CD8 T cell subset distribution and exhaustion markers (LAG-3, TIM-3 and PD-1) on T cells over time in SKOV3 cocultures. Data represent mean ± SD from three independent biological donors. Data are presented as mean ± SD, n = 3 (independent biological replicates). The statistical analysis was measured by paired two-tailed t tests. ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p ≤ 0.0001, and ns indicates no significance.
Mda Mb 468 Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mda-mb-468/MDA-MB-468/10__1038_slash_s41419___026___09242___7-214-1-4
Average 99 stars, based on 1 article reviews
mda mb 468 cell line - by Bioz Stars, 2026-10
99/100 stars
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mda-mb-468  (ATCC)
99
ATCC mda-mb-468
In vitro antitumor efficacy and effector function of mRNA CAR T cells (A) Enlarged schematic of the real-time cytotoxicity assessment (RTCA) workflow. (B) <t>Cytolysis</t> <t>of</t> <t>MDA-MB-468</t> cells at 24 h across various E:T ratios. (C and D) Cytokine secretion (IL-2, TNF-α, IFN-γ, and CD4/CD8 subset distribution). (E–G) Flow cytometry analysis of exhaustion markers. (H) Schematic illustration of the mechanism for mRNA-CAR delivery into T cells via lipid nanoparticles. (I) Cytolysis of SKOV3 cells at 24 h across various E:T ratios. (J) Supernatant cytokine secretion (IL-2, TNF-α, and IFN-γ) following coculture with SKOV3 cells. (K–N) Flow cytometry analysis of CD4/CD8 T cell subset distribution and exhaustion markers (LAG-3, TIM-3 and PD-1) on T cells over time in SKOV3 cocultures. Data represent mean ± SD from three independent biological donors. Data are presented as mean ± SD, n = 3 (independent biological replicates). The statistical analysis was measured by paired two-tailed t tests. ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p ≤ 0.0001, and ns indicates no significance.
Mda Mb 468, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mda-mb-468/MDA-MB-468/custom%40htb-132%4042472092
Average 99 stars, based on 1 article reviews
mda-mb-468 - by Bioz Stars, 2026-10
99/100 stars
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In vitro antitumor efficacy and effector function of mRNA CAR T cells (A) Enlarged schematic of the real-time cytotoxicity assessment (RTCA) workflow. (B) Cytolysis of MDA-MB-468 cells at 24 h across various E:T ratios. (C and D) Cytokine secretion (IL-2, TNF-α, IFN-γ, and CD4/CD8 subset distribution). (E–G) Flow cytometry analysis of exhaustion markers. (H) Schematic illustration of the mechanism for mRNA-CAR delivery into T cells via lipid nanoparticles. (I) Cytolysis of SKOV3 cells at 24 h across various E:T ratios. (J) Supernatant cytokine secretion (IL-2, TNF-α, and IFN-γ) following coculture with SKOV3 cells. (K–N) Flow cytometry analysis of CD4/CD8 T cell subset distribution and exhaustion markers (LAG-3, TIM-3 and PD-1) on T cells over time in SKOV3 cocultures. Data represent mean ± SD from three independent biological donors. Data are presented as mean ± SD, n = 3 (independent biological replicates). The statistical analysis was measured by paired two-tailed t tests. ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p ≤ 0.0001, and ns indicates no significance.

Journal: iScience

Article Title: Lipid-based mRNA chimeric antigen receptor T cells for enhanced in vitro antitumor activity

doi: 10.1016/j.isci.2026.117390

Figure Lengend Snippet: In vitro antitumor efficacy and effector function of mRNA CAR T cells (A) Enlarged schematic of the real-time cytotoxicity assessment (RTCA) workflow. (B) Cytolysis of MDA-MB-468 cells at 24 h across various E:T ratios. (C and D) Cytokine secretion (IL-2, TNF-α, IFN-γ, and CD4/CD8 subset distribution). (E–G) Flow cytometry analysis of exhaustion markers. (H) Schematic illustration of the mechanism for mRNA-CAR delivery into T cells via lipid nanoparticles. (I) Cytolysis of SKOV3 cells at 24 h across various E:T ratios. (J) Supernatant cytokine secretion (IL-2, TNF-α, and IFN-γ) following coculture with SKOV3 cells. (K–N) Flow cytometry analysis of CD4/CD8 T cell subset distribution and exhaustion markers (LAG-3, TIM-3 and PD-1) on T cells over time in SKOV3 cocultures. Data represent mean ± SD from three independent biological donors. Data are presented as mean ± SD, n = 3 (independent biological replicates). The statistical analysis was measured by paired two-tailed t tests. ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p ≤ 0.0001, and ns indicates no significance.

Article Snippet: The SKOV3 cell line was purchased from ATCC, while the DC2.4 and MDA-MB-468 cell lines were obtained from the Cell Bank of Chinese Academy of Sciences.

Techniques: In Vitro, Flow Cytometry, Analysis, Two Tailed Test

Journal: iScience

Article Title: Lipid-based mRNA chimeric antigen receptor T cells for enhanced in vitro antitumor activity

doi: 10.1016/j.isci.2026.117390

Figure Lengend Snippet:

Article Snippet: The SKOV3 cell line was purchased from ATCC, while the DC2.4 and MDA-MB-468 cell lines were obtained from the Cell Bank of Chinese Academy of Sciences.

Techniques: Recombinant, Saline, Modification, Virus, Filtration, Membrane, Cell Isolation, Software, FCAP Assay, Sequencing