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The synthesis process of phenylboronic-acid-functionalized oxidized sodium alginate and gallic-acid-conjugated chitosan (OSA-PBA/CS-GA) hydrogel and its multifunctional mechanisms in healing diabetic wounds. ROS, reactive oxygen species; SOD, superoxide dismutase; CAT, catalase; MDA, malondialdehyde; α-SMA, alpha smooth muscle actin; VEGF, vascular endothelial growth factor; IL-6, interleukin 6; MMP9, matrix metalloproteinase 9.

Journal: Biomaterials Research

Article Title: A Glucose-Responsive Hydrogel with Multifunctional Properties for Accelerated Diabetic Wound Healing

doi: 10.34133/bmr.0405

Figure Lengend Snippet: The synthesis process of phenylboronic-acid-functionalized oxidized sodium alginate and gallic-acid-conjugated chitosan (OSA-PBA/CS-GA) hydrogel and its multifunctional mechanisms in healing diabetic wounds. ROS, reactive oxygen species; SOD, superoxide dismutase; CAT, catalase; MDA, malondialdehyde; α-SMA, alpha smooth muscle actin; VEGF, vascular endothelial growth factor; IL-6, interleukin 6; MMP9, matrix metalloproteinase 9.

Article Snippet: Sections were incubated overnight at 4 °C with primary antibodies including matrix metalloproteinase 9 (MMP9; A0289), interleukin-6 (IL-6; A21264) (ABclonal, China), CD86 (30691-1-AP), CD206 (18704-1-AP) (Proteintech), CD31 (ab281583), vascular endothelial growth factor (VEGF; ab32152) (Abcam, UK), and alpha smooth muscle actin (α-SMA; A2235, ABclonal).

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