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Comparative analysis of fluconazole susceptibility between the Vitek-2 system and the disc diffusion method.

Journal: Frontiers in Fungal Biology

Article Title: Fluconazole resistance among Candida species with special emphasis on ERG11 gene mutations among Candida tropicalis

doi: 10.3389/ffunb.2025.1695271

Figure Lengend Snippet: Comparative analysis of fluconazole susceptibility between the Vitek-2 system and the disc diffusion method.

Article Snippet: Furthermore, a study conducted by Nadeen Jeddy et al. in Chennai, South India, reported a slightly higher fluconazole resistance rate of 10.5%, which might be attributed to local healthcare practices.

Techniques: Diffusion-based Assay

In vitro activity of the combination of fluconazole (8 µg/mL) and lactoferrin (8 µg/mL) against fluconazole resistant isolates ( a ) C. albicans UPV 15–147 and ( b ) C. albicans UPV 15–157; fluconazole resistant control strains ( c ) C. albicans ATCC 64124 and ( d ) C. parapsilosis NCPF 3153; and fluconazole susceptible control strains ( e ) C. albicans NCPF 3104 and ( f ) C. parapsilosis ATCC 22019

Journal: Annals of Clinical Microbiology and Antimicrobials

Article Title: Synergistic effect of lactoferrin combined with fluconazole to overcome antifungal resistance in Candida species

doi: 10.1186/s12941-025-00836-1

Figure Lengend Snippet: In vitro activity of the combination of fluconazole (8 µg/mL) and lactoferrin (8 µg/mL) against fluconazole resistant isolates ( a ) C. albicans UPV 15–147 and ( b ) C. albicans UPV 15–157; fluconazole resistant control strains ( c ) C. albicans ATCC 64124 and ( d ) C. parapsilosis NCPF 3153; and fluconazole susceptible control strains ( e ) C. albicans NCPF 3104 and ( f ) C. parapsilosis ATCC 22019

Article Snippet: The efficacy of the combination between fluconazole and lactoferrin was tested by means of time-kill curves against two clinical isolates of fluconazole resistant Candida , in which it was observed synergistic effect ( C. albicans UPV 15–147 and C. albicans UPV 15–157), two fluconazole resistant reference strains ( C. albicans ATCC 64124 and C. parapsilosis NCPF 3104), and two fluconazole susceptible reference strains ( C. albicans NCPF 3153 and C. parapsilosis ATCC 22019).

Techniques: In Vitro, Activity Assay, Control

In vitro activity of the combination of fluconazole (8 µg/mL) and lactoferrin (8 µg/mL) against fluconazole resistant isolates ( a ) C. albicans UPV 15–147 and ( b ) C. albicans UPV 15–157; fluconazole resistant control strains ( c ) C. albicans ATCC 64124 and ( d ) C. parapsilosis NCPF 3153; and fluconazole susceptible control strains ( e ) C. albicans NCPF 3104 and ( f ) C. parapsilosis ATCC 22019

Journal: Annals of Clinical Microbiology and Antimicrobials

Article Title: Synergistic effect of lactoferrin combined with fluconazole to overcome antifungal resistance in Candida species

doi: 10.1186/s12941-025-00836-1

Figure Lengend Snippet: In vitro activity of the combination of fluconazole (8 µg/mL) and lactoferrin (8 µg/mL) against fluconazole resistant isolates ( a ) C. albicans UPV 15–147 and ( b ) C. albicans UPV 15–157; fluconazole resistant control strains ( c ) C. albicans ATCC 64124 and ( d ) C. parapsilosis NCPF 3153; and fluconazole susceptible control strains ( e ) C. albicans NCPF 3104 and ( f ) C. parapsilosis ATCC 22019

Article Snippet: Fig. 1 In vitro activity of the combination of fluconazole (8 μg/mL) and lactoferrin (8 μg/mL) against fluconazole resistant isolates ( a ) C. albicans UPV 15–147 and ( b ) C. albicans UPV 15–157; fluconazole resistant control strains ( c ) C. albicans ATCC 64124 and ( d ) C. parapsilosis NCPF 3153; and fluconazole susceptible control strains ( e ) C. albicans NCPF 3104 and ( f ) C. parapsilosis ATCC 22019

Techniques: In Vitro, Activity Assay, Control