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Journal: Frontiers in Endocrinology
Article Title: Quantitative Ubiquitinomics Revealed Abnormal Ubiquitinated ATP7A Involved in Down-Regulation of ACTH in Silent Corticotroph Adenomas
doi: 10.3389/fendo.2022.863017
Figure Lengend Snippet: Function of ATP7A in AtT20 cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the ACTH level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.
Article Snippet: AtT20 cells treated with omeprazole (HY-B0113A,
Techniques: Knockdown, Control
Journal: Journal of Functional Foods
Article Title: Juglanin ameliorates depression-like behavior in chronic unpredictable mild stress-induced mice by improving AMPK signaling
doi: 10.1016/j.jff.2022.105263
Figure Lengend Snippet: Fig. 2. Effects of Juglanin on depression-related hormones in CUMS-challenged mice. (A) 5-HTP contents in serum. (B) 5-HT levels in hippocampus samples. CORT contents in (C) Serum and (D) hippocampal tissues. (E) Serum ACTH levels. (F) DA contents, (G) GABA levels and (H) glutamate concentrations in hippocampal samples from each group of mice. All data are shown as the mean ± SEM (n = 8 per group). *p < 0.05 and **p < 0.01 vs the Con/Veh group; +p < 0.05 and ++p < 0.01 vs the CUMS/Veh group.
Article Snippet:
Techniques: