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MedChemExpress acth levels
Function of ATP7A <t>in</t> <t>AtT20</t> cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the <t>ACTH</t> level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.
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Function of ATP7A <t>in</t> <t>AtT20</t> cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the <t>ACTH</t> level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.
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Function of ATP7A <t>in</t> <t>AtT20</t> cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the <t>ACTH</t> level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.
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Function of ATP7A <t>in</t> <t>AtT20</t> cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the <t>ACTH</t> level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.
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Function of ATP7A <t>in</t> <t>AtT20</t> cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the <t>ACTH</t> level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.
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Function of ATP7A <t>in</t> <t>AtT20</t> cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the <t>ACTH</t> level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.
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Function of ATP7A <t>in</t> <t>AtT20</t> cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the <t>ACTH</t> level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.
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Elabscience Biotechnology mouse adrencocorticotropic hormone acth levels
Fig. 2. Effects of Juglanin on depression-related hormones in CUMS-challenged mice. (A) 5-HTP contents in serum. (B) 5-HT levels in hippocampus samples. CORT contents in (C) Serum and (D) hippocampal tissues. (E) Serum <t>ACTH</t> levels. (F) DA contents, (G) GABA levels and (H) glutamate concentrations in hippocampal samples from each group of mice. All data are shown as the mean ± SEM (n = 8 per group). *p < 0.05 and **p < 0.01 vs the Con/Veh group; +p < 0.05 and ++p < 0.01 vs the CUMS/Veh group.
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Fig. 2. Effects of Juglanin on depression-related hormones in CUMS-challenged mice. (A) 5-HTP contents in serum. (B) 5-HT levels in hippocampus samples. CORT contents in (C) Serum and (D) hippocampal tissues. (E) Serum <t>ACTH</t> levels. (F) DA contents, (G) GABA levels and (H) glutamate concentrations in hippocampal samples from each group of mice. All data are shown as the mean ± SEM (n = 8 per group). *p < 0.05 and **p < 0.01 vs the Con/Veh group; +p < 0.05 and ++p < 0.01 vs the CUMS/Veh group.
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Eagle Biosciences serum acth levels
Fig. 2. Effects of Juglanin on depression-related hormones in CUMS-challenged mice. (A) 5-HTP contents in serum. (B) 5-HT levels in hippocampus samples. CORT contents in (C) Serum and (D) hippocampal tissues. (E) Serum <t>ACTH</t> levels. (F) DA contents, (G) GABA levels and (H) glutamate concentrations in hippocampal samples from each group of mice. All data are shown as the mean ± SEM (n = 8 per group). *p < 0.05 and **p < 0.01 vs the Con/Veh group; +p < 0.05 and ++p < 0.01 vs the CUMS/Veh group.
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Image Search Results


Function of ATP7A in AtT20 cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the ACTH level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.

Journal: Frontiers in Endocrinology

Article Title: Quantitative Ubiquitinomics Revealed Abnormal Ubiquitinated ATP7A Involved in Down-Regulation of ACTH in Silent Corticotroph Adenomas

doi: 10.3389/fendo.2022.863017

Figure Lengend Snippet: Function of ATP7A in AtT20 cells. (A) The intensity of ubiquitinated peptides of ATP7A in SCAs and FCAs. (B) Up-regulation of the ACTH level in AtT20 cells with the knockdown of ATP7A by ATP7A siRNA. (C) Up-regulation of the ACTH level in AtT20 cells treated with 20uM omeprazole. All assays were performed in triplicate. (D) The top 20 potential E3 ligases of ATP7A. *Compared to control, p < 0.05.

Article Snippet: AtT20 cells treated with omeprazole (HY-B0113A, MedChemExpress) and the ACTH levels were assessed by an enzyme-linked immunosorbent assay (ELISA) (SBJ-M0483, SBJbio) according to the manufacture’s protocol.

Techniques: Knockdown, Control

Fig. 2. Effects of Juglanin on depression-related hormones in CUMS-challenged mice. (A) 5-HTP contents in serum. (B) 5-HT levels in hippocampus samples. CORT contents in (C) Serum and (D) hippocampal tissues. (E) Serum ACTH levels. (F) DA contents, (G) GABA levels and (H) glutamate concentrations in hippocampal samples from each group of mice. All data are shown as the mean ± SEM (n = 8 per group). *p < 0.05 and **p < 0.01 vs the Con/Veh group; +p < 0.05 and ++p < 0.01 vs the CUMS/Veh group.

Journal: Journal of Functional Foods

Article Title: Juglanin ameliorates depression-like behavior in chronic unpredictable mild stress-induced mice by improving AMPK signaling

doi: 10.1016/j.jff.2022.105263

Figure Lengend Snippet: Fig. 2. Effects of Juglanin on depression-related hormones in CUMS-challenged mice. (A) 5-HTP contents in serum. (B) 5-HT levels in hippocampus samples. CORT contents in (C) Serum and (D) hippocampal tissues. (E) Serum ACTH levels. (F) DA contents, (G) GABA levels and (H) glutamate concentrations in hippocampal samples from each group of mice. All data are shown as the mean ± SEM (n = 8 per group). *p < 0.05 and **p < 0.01 vs the Con/Veh group; +p < 0.05 and ++p < 0.01 vs the CUMS/Veh group.

Article Snippet: Mouse adrencocorticotropic hormone (ACTH) levels in serum were examined using a commercial ELISA Kit (#E-EL-M0079c; Elabscience, Wuhan, China).

Techniques: