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Copy number status and fragment orientation as revealed by chromosomal microarray (CMA) and whole genome sequencing (WGS) of the complex rearrangements.

Journal: PLoS Genetics

Article Title: Replicative and non-replicative mechanisms in the formation of clustered CNVs are indicated by whole genome characterization

doi: 10.1371/journal.pgen.1007780

Figure Lengend Snippet: Copy number status and fragment orientation as revealed by chromosomal microarray (CMA) and whole genome sequencing (WGS) of the complex rearrangements.

Article Snippet: In 13 cases (P2046_133, P2109_123, P2109_150, P2109_151, P2109_162, P2109_188, P2109_190, P2109_302, P4855_511, P4855_512, P2109_176, P1426_301, P2109_185), the CMA was performed with an 180K custom oligonucleotide microarray with whole genome coverage and a median resolution of approximately 18 kb (Oxford Gene Technology (OGT), Oxfordshire, UK).

Techniques: Microarray, Sequencing