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Chemokines expression level in tissue-specific macrophages (log 2 TPM) RNA-Seq datasets were collected from ArrayXpress of European Bioinformatics Institute, which stores data from high-throughput functional genomics experiments ( https://www.ebi.ac.uk/arrayexpress ). These data include information on the expression of T-cell costimulation receptors and coinhibition receptors through experiments submitted directly to ArrayXpress (PMID: 25480296). The red colour indicated log 2 TPM > 0, green colour background indicated log 2 TPM < 0.

Journal: CJC Open

Article Title: Chemokine Ligands and Receptors Regulate Macrophage Polarization in Atherosclerosis: A Comprehensive Database Mining Study

doi: 10.1016/j.cjco.2024.11.018

Figure Lengend Snippet: Chemokines expression level in tissue-specific macrophages (log 2 TPM) RNA-Seq datasets were collected from ArrayXpress of European Bioinformatics Institute, which stores data from high-throughput functional genomics experiments ( https://www.ebi.ac.uk/arrayexpress ). These data include information on the expression of T-cell costimulation receptors and coinhibition receptors through experiments submitted directly to ArrayXpress (PMID: 25480296). The red colour indicated log 2 TPM > 0, green colour background indicated log 2 TPM < 0.

Article Snippet: In this study, data on chemokine ligands and receptors were obtained by mining public databases (the National Center of Biotechnology Information-Gene Expression Omnibus [NCBI-GEO] database, ArrayExpress database, and single-cell RNA sequencing [scRNA-seq] database), and an extensive literature search was performed.

Techniques: Expressing, RNA Sequencing, High Throughput Screening Assay, Functional Assay